Factors Impacting Online Learning Usage during Covid-19 Pandemic Among Sophomores in Sichuan Private Universities

Purpose: This study aims to examine factors impacting online learning usage among students in Sichuan private universities, China. The variables used to construct the conceptual framework are perceived ease of use, perceived usefulness, information quality, system quality, service quality, attitude towards using, satisfaction, behavioral intention and actual use. Research design, data and methodology: The quantitative approach (n=500) was conducted via online questionnaire, using judgmental sampling, quota sampling and convenience sampling. Before processing the data collection, content validity was reserved by index of item objective congruence (IOC). Pilot study of 40 samples was approved by Cronbach's Alpha reliability test. Afterwards, the data was analyzed in SPSS using descriptive statistics, confirmatory factor analysis (CFA) and structural equation modeling (SEM). Results: The results revealed that satisfaction had the strongest significant impact on behavioral intention, followed by perceived usefulness on attitude toward using, service quality on behavioral intention, behavioral intention on actual use, information quality on behavioral intention, perceived ease of use on attitude toward using and attitude toward using on behavioral intention. On the other hand, the relationship between system quality and behavioral intention was not significant. Conclusions: Academic practitioners were recommended to encourage online learning usage among students by developing better online learning system, technical support service and learning experience which led to successful adoption and learning effectiveness of students in higher education.

Study on Spatial Changes in PM2.5 before and after the COVID-19 Pandemic in Southwest China

Coronavirus disease 2019 (COVID-19) swept the world at the beginning of 2020, and strict activity control measures were adopted in China's concentrated and local outbreak areas, which led to social shutdown. This study was conducted in southwest China from 2019 to 2021, and was divided into the year before COVID-19 (2019), the year of COVID-19 outbreak (2020), and the year of normalization of COVID-19 prevention and control (2021). A geographically and temporally weighted regression (GTWR) model was used to invert the spatial distribution of PM2.5 by combining PM2.5 on-site monitoring data and related driving factors. At the same time, a multiple linear regression (MLR) model was constructed for comparison with the GTWR model. The results showed that: (1) The inversion accuracy of the GTWR model was higher than that of the MLR model. In comparison with the commonly used PM2.5 datasets "CHAP” and "ACAG”, PM2.5 inverted by the GTWR model had higher data accuracy in southwest China. (2) The average PM2.5 concentrations in the entire southwest region were 32.1, 26.5, and 28.6 μg/m3 over the three years, indicating that the society stopped production and work and the atmospheric PM2.5 concentration reduced when the pandemic control was highest in 2020. (3) The winter and spring of 2020 were the relatively strict periods for pandemic control when the PM2.5 concentration showed the most significant drop. In the same period of 2021, the degree of control was weakened, and the PM2.5 concentration showed an upward trend.

Changes of atmospheric metal(loid) deposition from 2017 to 2021 at Mount Emei under China's air pollution control strategy

Acid deposition and particulate matter (PM) pollution have declined considerably in China. Although metal(loid) and acid deposition and PM have many common sources, the changes of metal(loid) deposition in China in the recent decade have not been well explored by using long-term monitoring. Therefore, we analyzed the dry and wet deposition of eleven metal(loid)s (including Al, As, Ba, Cd, Cu, Cr, Fe, Mn, Pb, Sr, and Zn) from 2017 to 2021 at Mount Emei, which is adjacent to the most economic-developed region in western China (Sichuan Basin (SCB)). Anthropogenic emissions contributed to over 80% of the annual wet deposition fluxes of metal(loid)s and acids (SO4 2-, NO3 -, and NH4 +) at Mount Emei, and the major source regions were the SCB, the Yunnan-Guizhou Plateau, and Gansu Province. Metal(loid) and acid deposition had similar seasonal variations with higher wet deposition fluxes in summer but higher wet deposition concentrations and dry fluxes in winter. The seasonal variations were partially associated with higher precipitation but lower pH in summer (968 mm and 5.52, respectively) than in winter (47 mm and 4.73, respectively). From 2017 to 2021, metal(loid) deposition did not decline as substantially as acid deposition (5.6%-30.4%). Both the annual total deposition fluxes and concentrations of Cr, Cu, Sr, Ba, and Pb were even higher in 2020-2021 than in 2017-2018. The inter-annual and seasonal changes implied the responses of metal(loid) deposition to anthropogenic emission changes were buffered (e.g., transformation, dilution, and degradation) by precipitation rates, acidity, natural emissions, and chemical reactions in the atmosphere, among others.Copyright © 2023 Elsevier Ltd

Isolation, identification and genetic evolution analysis of porcine epidemic diarrhea virus SNJ-P strain in Sichuan Province

Purpose: To investigate the epidemic variation of porcine epidemic diarrhea virus (PEDV) strains in Sichuan Province, and to analyze the causes of poor vaccination effect. Methods: Piglet intestinal samples were collected from a pig farm in Sichuan Province for PCR detection, virus purification, determination of virus titer and virus infection experiments. Whole genome sequencing of isolated strains was determined. The S gene sequence of the isolated strain was compared with the strains from other regions and vaccine strains, and the phylogenetic tree was established. The amino acid site variation of S protein between the isolated strain and the classical vaccine strain CV777 was compared. Results: A PEDV strain was successfully isolated and named as PEDV SNJ-P. The determination of virus titer was 1..107.5/100 L. Animal infection experiments showed that the isolated strain could cause diarrhea, dehydration and other symptoms and lead to death in piglets. Genome sequencing and phylogenetic tree analysis showed that the whole gene of PEDV SNJ-P strain was 28003 bp, and the genotype of the strain was S non-INDEL type. The strains were closely related to the strains of PEDV-WS, CH/JLDH/2016 and CH/HNLH/2015 isolated from China, and were relatively distant with the same type vaccine strain, and were far from the classical vaccine strain. Compared with the classical vaccine strain CV777, the S protein of SNJ-P strain had multiple amino acid mutations, deletions and insertions. Conclusion: Due to the continuous variation of strains, SNJ-P strain is far from the vaccine strain, and the current vaccines cannot provide effective protection. The results of this study are expected to provide reference for the study of PEDV strains and vaccine development in China.

Awareness and needs of parents regarding pediatric infectious diseases in kindergartens in Chenghua District of Chengdu

Objective: To understand the awereness and health needs of parents in regards to infectious diseases in kindergartens in Chengdu, and to provide a reference for carrying out targeted health education on infectious diseases. Methods: The parents of kindergarten children in Chenghua District of Chengdu was selected by convenient sampling, and a self-designed questionnaire was used. Results: The rate of awareness among parents regarding pediatric infectious diseases was 42.0%, among which the awareness rate of "treatment measures following a dog bite" was the highest (99.6%), and "the awareness rate of infectious disease classifications in China" was the lowest (26.7%). The awareness rate was related to family role, education level, occupation and income level (X2=10.81, 71.81, 93.78, 25.17, P < 0.05). The survey examined the demand for knowledge regarding pediatric infectious disease prevention and control, and revealed that parents primarily obtained such information from the school class group (85.5%). The most desirable way of obtaining relevant information was from information provided by professional institutions (96.6%), the infectious disease that parents most wanted to know about was the 2019 novel coronavirus (91.9%), and the most desirable time to acquire knowledge about infectious diseases depended on the seasonal arrangement of infectious diseases (67.5%). Conclusion: The awareness rate of parents about children's infectious diseases is in the middle level, and the channels for acquiring the knowledge about infectious diseases are relatively limited. Schools can carry out targeted health education in order to raise the awareness rate of parents of preschool children about children's infectious diseases.

Reduced pain intensity at the first dressing improves postoperative pain control after anorectal surgery

This study aimed to investigate the effects of first dressing changes on the postoperative pain intensity and the duration of pain in patients after anorectal surgeries to provide evidence for improving postoperative pain control. A total of 164 patients with an anorectal disease scheduled to undergo surgery were enrolled in this study, and their postoperative pain levels and duration were recorded. The status of severe pain for a rating score 7 during hospitalization after surgery was considered as the study endpoint. The pain score at the first dressing change was recorded and considered a potential risk factor for predicting severe pain during hospitalization by logistic regression analysis. Comparisons of postoperative pain outcomes between patients with a pain rating score 7 or <7 were performed before and after propensity score matching. Severe pain (rating score 7) at the first dressing change was an independent risk factor for severe pain during hospitalization (odds ratio (OR) = 8.33, p < 0.001). Pain on the first night after surgery in the Severe group was higher than in the Non-Severe group (3.2 +or- 0.9 vs. 2.8 +or- 1.0, p = 0.006). Patients in the Severe group had higher pain number rating scale (NRS) scores at the second (5.2 +or- 1.3 vs. 3.1 +or- 1.2, p < 0.001) and third (3.5 +or- 1.5 vs. 1.9 +or- 0.9, p < 0.001) dressing change than those in the Non-Severe group. Moreover, the overall NRS pain score during hospitalization in the Severe group was significantly higher than the Non-Severe group (5.7 +or- 1.1 vs. 3.9 +or- 1.5, p < 0.001), and the incidence of severe postoperative pain during hospitalization was also higher (61.6% vs. 12.1%, p < 0.001). In addition, pain duration in the Severe group was significantly longer than in the Non-Severe group (10 (3, 18) vs. 5 (2, 10), p < 0.001). Regarding the distributions of propensity scores, the overall NRS pain score during hospitalization in the Severe group was significantly higher than in the Non-Severe group (5.7 +or- 1.1 vs. 3.8 +or- 1.4, p < 0.001), as well as a higher incidence in severe postoperative pain (61.2% vs. 7.5%, p < 0.001), which was accompanied by a significantly longer pain duration in the Severe group (10 (3, 18) vs. 5 (2, 10), p < 0.001). Moreover, subgroup analysis showed that patients in the Severe group had higher overall pain NRS scores than the Non-Severe group for both the Milligan-Morgan (5.6 +or- 1.5 vs. 4.0 +or- 1.1, p < 0.001) and Thread-ligating (5.8 +or- 1.4 vs. 3.9 +or- 1.0, p < 0.001) surgery groups. Pain intensity at the first dressing change was sociated with the intensity and duration of postoperative pain in patients who underwent anorectal surgery. Thus, proper actions are needed to relieve the pain intensity at the first dressing change.

Observation of changes of early laboratory indicators and COVID-19 vaccine protection in patients infected with SARS-CoV-2 Delta variant

Objective: To observe early laboratory indicators in peripheral blood of patients infected with SARSCoV- 2 Delta variant and the protective effects of COVID-19 vaccine on patients infected with SARS-CoV-2 Delta variant, in order to provide reference for epidemic prevention and control. Methods: Twenty-five Chengdu local confirmed nonsevere COVID-19 patients over 18 years old who were infected with COVID-19 caused by Delta variant in November 2021 were included as the research group, 22 cases of whom were vaccinated with COVID-19 vaccine before infection, and 3(2 cases over 80 years old)were unvaccinated. In addition, 71 non-severe COVID-19 patients at the age of over 18 years diagnosed in Chengdu from January 2020 to February 2020 were included as the control group. Peripheral blood was collected for laboratory examination in all cases on the first or second days after admission, and peripheral blood was collected for laboratory examination again in patients on day 4 to 8 after admission in the research group. Laboratory indicators included the blood routine, C-reactive protein, procalcitonin, liver function, myocardial enzyme profile, coagulation routine, T lymphocyte subsets, SARS-CoV-2 IgG antibody, and total antibody, etc. The first peripheral blood laboratory test results: of the two groups were compared to observe the protective effect of COVID-19 vaccine on patients infected with SARS-CoV- 2 Delta variant. Results Among the first time of laboratory indicators after admission, the lymphocyte count, lactate dehydrogenase, and D-dimer in the research group were all lower than those in the control group(all P < 0.05), and the procalcitonin and aspartate aminotransferase were higher than those in the control group(all P < 0.05). Among the 22 cases who had gotten vaccine before infection in the research group, there were 5 cases with positive result of SARS-CoV-2 IgG antibody in the first time of peripheral blood, 22 cases with positive result of SARS-CoV-2 IgG antibody in the second time of peripheral blood, and none of them became severe cases. During 3 unvaccinated cases, twice of the SARS-CoV-2 IgG antibody were both negative among the 2 cases over 80 years who had not vaccinated in the research group, then they became severe cases on day 6-8 during hospitalization, and the rest one had negative result of SARS-CoV-2 IgG antibody in the second time of peripheral blood. Among the 22 vaccinated cases in the research group, the lymphocyte count, CD4+T cell count, CD8+T cell count, SARS-CoV-2 specific antibodies in the second time peripheral blood were all higher than those in the first time of peripheral blood(all P < 0.05), and platelet count, hemoglobin, total protein, creatine kinase were all lower than those in the first time of peripheral blood(all P < 0.05). Conclusions: Lymphocyte count at early admission in COVID-19 patients infected with Delta variant may be lower than that infected with wild strain. COVID-19 vaccine can reduce the risk of infection of SARS-CoV-2 Delta variant by preventing the emergence of inflammatory storms and producing a large number of specific antibodies.

Whole genome sequence analysis of SARS-CoV-2 from 40 imported cases of confirmed COVID-19 in Sichuan

Objective: To understand the genomic characteristics of SARS-CoV-2 from 40 imported cases with confirmed COVID-19 in Sichuan during January and March 2022. Methods: Total viral RNA was extracted from respiratory samples of 182 confirmed COVID-19 cases who entered China through Chendu International Airport from January to March 2022. Mutation nucleic acid detection kit was used to identify the mutant strains and Illumina sequencing platform was applied for whole genome sequence(WGS) of virus. SARS-CoV-2 reference sequences were downloaded from NCBI database for genetic evolution and antigen variation analysis. The Nextclade and Pangolin online virus analysis platform were used to determine the virus family and type, and to analyze the mutation loci of the virus. The phylogenetic tree was constructed, along with the epidemiological data of cases to analyze the source and correlation of viruses. Results: Among 182 imported COVID-19 cases,B.1.617.2 mutations were identified in 3 cases and B.1.1.529 mutations were detected in 57 cases.A total of 40 SARS-CoV-2 whole genome sequences with coverage>95% were obtained in this study. Nextclade typing analysis showed that 3 sequences belonged to 21J(Delta),5 sequences belonged to 21K(Omicron)and the remaining 32 sequences belonged to 21L(Omicron). Pangolin typing analysis showed that the 3 sequences of 21J(Delta)belonged to AY.4,AY.109and B.1.617.2, the 5sequences of 21K(Omicron)all belonged to BA.1.1, and the remaining 32 sequences of 21L(Omicron)belonged to BA.2. Our sequence results were99.7% consistency with the Omicron variants sequences in current GISAID database. Compared with the reference sequence strain Wuhan-Hu-1(NC_045512.2),45,47and 42nucleotide variation sites and 36,25 and 36amino acid variation sites were found in the 3 sequences of 21J(Delta). There were average 59(26-64)nucleotide mutation sites and 48(10-53)amino acid mutation sites in the 5sequences of 21K(Omicron). The median number of nucleotide mutation sites of 71(66-76)and amino acid mutation sites of 53(40-56)were identified in the 32sequences of 21L(Omicron). Phylogenetic tree analysis showed that 40SARS-CoV-2WGSs were all related to the current variants of concern(VOC). Conclusions Continuous: sequencing of SARS-CoV-2whole genome from imported cases with confirmed COVID-19is of great significance for the prevention and control of the outbreak and prevalence of local epidemic caused by imported viruses in Sichuan.

The effect of overweight or obesity on the negative conversion time of SARS-CoV-2 nucleic acid

Objective To investigate the relationship between the body mass index (BMI) levels and the negative conversion time of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid in adult coronavirus disease 2019 (COVID-19) patients and the asymptomatic persons. Methods Asymptomatic infected patients and confirmed COVID-19 patients admitted to Chengdu Public Health Clinic Center from February 2021 to November 2021 were dynamically included. The epidemiological and clinical characteristics of the objects were collected, and the SARS-CoV-2 nucleic acid testing of the objects during their hospitalization was continuously monitored, and the negative nucleic acid conversion time was recorded. The t test or Wilcoxon rank sum test, X 2 test or Fisher's exact probability method examine were used to distribute characteristics of each group of variables and the connection between different variables, respectively. Then the variables showed differences in distribution (P < 0.05) between different BMI groups were included in the multivariate Cox proportional risk regression model. Results A total of 253 subjects ranged from 18 to 63 years old, with M(P25, P75) age of 37.0 (30.0, 47.0) years old, were included in this study. The male to female ratio was 4.16 to 1. The BMI was (23.97+or-3.33) kg/m2. 50.59% (128/253) of the objects were overweight or obese, and 78.13% (100/128) were overweight. The negative time of SARS-CoV-2 nucleic acid conversion of all subjects ranged from 1 to 71 days, with M(P25, P75) of 7.0 (2.0, 18.0) days (P < 0.001). The negative time of SARS-CoV-2 nucleic acid conversion of the normal weight or the thin, and the overweight or obese were 5.00 (2.00, 19.00) and 8.00 (2.00, 17.75) days respectively. The results of multivariate Cox's proportional hazards regression model showed that the BMI levels may not be associated with the negative conversion time of SARS-CoV-2 nucleic acid (HR=1.090, 95%CI: 0.843-1.410, P=0.510). Conclusions Adult asymptomatic persons and confirmed COVID-19 patients are mainly middle-aged and young males, and overweight or obesity is relatively common. Overweight or obesity cannot be considered as an independent factor influencing the negative conversion time of SARS-CoV-2 nucleic acid.

Epidemiological characteristics of influenza in Mianyang, Sichuan, 2019-2021

Objective: To understand the epidemiological and etiological characteristics of influenza in Mianyang City from 2019 to 2021, so as to provide a basis for the prevention and control of influenza. Methods: Influenza surveillance data in Mianyang City from 2019 to 2021 were collected and analyzed statistically. Results: A total of 55 970 cases of influenza were reported in Mianyang City from 2019 to 2021, with an average annual incidence of 388.08/100 000. A total of 103 723 cases of influenza-like illness cases (ILI) were reported, with an average annual ILI% of 3.58%. The incidence, ILI%, and positive detection rates of influenza were all far higher than those in the corresponding period in 2019. The classification of the population is mainly composed of students under the age of 15. The top three reported cases were Fucheng District (20 118, 35.94%), Youxian District (6 394, 11.42%) and Jiangyou District (5 800, 10.36%). 10 126 samples of ILI were received and detected, with a positive rate of 19.53%, the positive rate of ILI samples was mainly students under 15 years old. The dominant strains of influenza viruses showed an alternating trend over the years, and A (H3) was the predominant type in 2019. Except for 2 A (H9) strains detected in 2021, the rest were all BV strains. Due to the impact of COVID-19 in 2020, the positive detection rate was low throughout the year. 43 outbreaks of ILI were reported, which were mainly occurred in winter, and most of them were in primary schools. Conclusion: From 2019 to 2021, the characteristics of cases, ILI, pathogen surveillance and outbreak events of influenza in Mianyang City are basically the same, with students under 15 years of age and schools remaining the key population and sites of concern. the importance of non-pharmaceutical interventions for influenza prevention and control is further evidenced by the low incidence of influenza during the COVID-19 pandemic.

COVID-19 moderates the association between to-metro and by-metro accessibility and house prices

Previous studies extensively examined the role of accessibility to metro in shaping house prices but largely overlooked the contribution of accessibility by metro. In addition, limited studies examined the moderating effect of COVID-19 on the price effects of to-metro and by-metro accessibility. Based on multilevel hedonic price and quantile regression models, this study scrutinizes the association between to-metro accessibility, by-metro accessibility, and house prices in Chengdu, China, and examines the moderating role of COVID-19 in this association. We show that by-metro accessibility significantly influences house prices. COVID-19 significantly influences the value of to-metro accessibility but marginally affects that of by-metro accessibility. The value of to-metro accessibility is disproportionately affected by the pandemic. Specifically, small or low-priced houses are less affected than big or high-priced houses. In other words, the flattening of the to-metro price gradient is more discernible for big or high-priced houses. The changing preference of residents has also been verified by the decreases in house transaction volume in metro-adjacent areas. © 2022 Elsevier Ltd

Study on TOD urban design method at district level from the perspective of resilient city

During the novel coronavirus epidemic from 2020 to the present, various cities have experienced different degrees of prevention, control and residents living problems. Taking the subway station area of Sichuan Normal University as an example, based on the theory of resilient city, this paper puts forward a conceptual TOD urban design strategy for the city to cope with sudden public health problems, studies the concept, development context and theoretical connotation of resilient city, and analyzes three types of application logic of resilient city in urban design of TOD area. Based on the analysis of the site basic conditions and users in the subway station area of Sichuan Normal University, the design result of "TOD Healthy Life Mode" combined with the concept of "Health + " is obtained, and the life trajectories of four types of users, including students, office workers, retired elderly and purpose visitors, are simulated. © 2022 Science Press. All rights reserved.

What attributes influence rural household's willingness to get vaccinated for COVID-19? Perspectives from six Chinese townships.

Since the onset of the COVID-19 pandemic, vaccinations have been identified as the most effective mitigation strategy against the deadly virus. This has led developed nations to accelerate research and shorten the licensure process for COVID-19 vaccines, but these changes have caused widespread concerns about vaccine safety. Research literature has long indicated that citizens' perceptions of protective actions will determine their behaviors, and thus, the relationship between vaccine perception and vaccination intention needs to be assessed. To better understand vaccination willingness, especially in rural populations, this study surveyed 492 households from six townships in the Ya'an region of China's Sichuan Province in November 2020. The survey followed the Protective Action Decision Model (PADM) framework for collecting perceptions about the influenza and COVID-19 vaccines as protective actions, information sources, emergency preparedness, emotional response, and demographic characteristics. The results showed that influenza vaccine perceptions significantly affected people's COVID-19 vaccination perceptions and intentions. Unlike previous vaccination willingness and other COVID-19 studies, this study found that perceptions of resource-related attributes and health-related attributes both affected COVID-19 vaccination intentions, but the former were slightly stronger than the latter. Moreover, these effects were strongest among respondents who had the most positive perceptions of their influenza vaccine experience. This study's findings will benefit local authorities in designing appropriate policies and measures (e.g., hazard education, risk communication, vaccination convenience enhancement) for increasing vaccination compliance for the current and future pandemics.

Bio-monitoring of atmospheric heavy metal pollution of major emergency events using moss bags:a case study in Xichang

In order to trace and monitor the atmospheric heavy metal pollution in Xichang City, an investigation activity was carried out with a sort of moss (Taxiphyllum taxirameum) (packed in moss bags) as a biological indicator for monitoring heavy metal pollution. The investigation was conducted from the period from April 2019 to April 2020, during which two grave emergency events occurred during spring monitoring period from January 15 to April 15, 2020, i.e., COVID-19 and "3.30"severe forest fire in Xichang, which inevitably affected the atmospheric quality. Based on the concentration analysis of 12 kinds of heavy metal, including Al, Cr, Fe, Cu, Ni, Pb, Mn, Hg, Zn, V, As and Ba contained in the moss and the local meteorological data, comparing those informative data before and after the time when the emergency events toke place, the paper made an analysis on the impacts of two enormous emergency events on the air pollution of heavy metal in Xichang. The results showed that total amount of enrichment of above-mentioned 12 heavy metals in spring (January 15 to April 15, 2020) is (12.85 +or- 1.57) mg/g, which was significantly higher than in the other three seasons (p < 0.01), but no significant discrepancies about the total enrichment amount in the other three seasons (p > 0.05). Primarily because of COVID-19 pandemic, the level of motor vehicles emissions cut down, and the decrease of the tourism in the related areas perhaps causing the decline of pollution of Pb. In addition, the decrease of unbalanced emission of pollutants led to a noted increase of atmospheric oxidation in urban area, thus boosting the formation of secondary particulate matter, and the particulate matter from surrounding industrial sources was transported into the urban area;as a result, remarkable increases of Hg concentration of moss within the moss bags were detected downwind the industrial area located in the urban fringe. Consequently, the investigation showed that the moss-bag method is an effective biological tool for monitoring air heavy metal pollution, which could reflect the impacts of major pollution events on air quality.

Spatiotemporal Characteristics and Influencing Factors of Tourism-Urbanization-Technology-Ecological Environment on the Yunnan-Guizhou-Sichuan Region: An Uncoordinated Coupling Perspective.

The tourism, urbanization, technology, and the ecological environment both promote and restrict each other. Coordinating the relationship between the four is of great significance to the realization of high-quality sustainable regional development. Taking the Yunnan-Guizhou-Sichuan region as an example, this paper constructs an uncoordinated coupling model for the tourism-urbanization-technology-ecological environment system. Using exploratory spatial analysis and geographic information systems, this paper reveals the temporal and spatial evolution law affecting the uncoordinated coupling relationship between tourism, urbanization, technology and the ecological environment in the Yunnan-Guizhou-Sichuan region from 2010 to 2020, before establishing a panel Tobit model that is used to explore the factors affecting the four systems. The research shows the following: (1) The level of comprehensive development for tourism, urbanization, technology, and the ecological environment in Yunnan, Guizhou, and Sichuan has increased rapidly. Of all these, the tourism industry was the most affected by COVID-19 in 2020, while the level of urbanization, technology, and ecological environment developments in the three provinces has become similar over time. (2) Uncoordinated development between cities is a prominent problem; while the uncoordinated coupling spatial agglomeration in various regions is relatively stable, the proportion of cities with no significant agglomeration form amounts to more than 70%, with mostly low-low (L-L) and high-high (H-H) agglomeration types. (3) The degree to which uncoordinated coupling exists among the four systems in the Yunnan-Guizhou-Sichuan region is affected by many factors. Only eco-environmental pressure has a significant positive correlation with the degree of uncoordinated coupling, while the tourism scale, economic urbanization, eco-environmental response, and investment in technology have a significant negative correlation. These results provide a theoretical basis and practical references for strengthening the government's macro-control and promoting collaborative regional development.

Study on the Dilemma and Countermeasures of Rural Emergency Management Under COVID-19—A Case Analysis Based on the Rural Areas Around Chengdu

The COVID-19 broke out and spread rapidly, posing a great challenge to the emergency management capacity of various regions in China, especially in rural areas. This paper takes three communities in ShiYang town, Dujiangyan City, Sichuan Province as cases, to analyze the specific practice of rural response to public health emergencies, summarize different stages in epidemic prevention and control, and explore the difficulties and solutions in rural emergency management. Through the case analysis, it is found that the rural epidemic prevention and control in ShiYang Town have experienced four stages including exploration period, development period, improvement period, and maturity period. At the same time, there are some dilemmas in rural emergency management, such as the imperfect emergency management mechanism, insufficient resources guarantee, and villagers’ weak awareness of health and epidemic prevention. Therefore, the paper proposes such countermeasures suggestions as improving the emergency management mechanism of rural public health, optimizing the resources guarantee system for rural emergency management, strengthening the popularization of health education, providing theoretical and practical guidance for improving the level of rural emergency management, and then promoting the modernization of rural emergency management system and capacity. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

Analysis on Cooperation Relationship of Poverty Alleviation Organizations in Sichuan Province Based on Link Prediction

Poverty eradication is the common ideal of mankind. Currently, as COVID-19 continues to rage around the world, the cause of poverty reduction faces greater challenges. Poverty reduction requires the involvement of multiple parties, and the challenging nature of it determines the complexity of participation in poverty reduction cooperation. In this paper, the link prediction method is used to calculate the path similarity in the network and use the Katz index to predict the connection possibility between unknown links in the poverty alleviation network. Take Sichuan Province as a case to analyze and put forward cooperation suggestions. The results show that in the entire network, all anti-poverty organizations recommend cooperation with one of the government departments, local schools, state-owned enterprises and high quality schools. Among them, government departments and local schools are the most recommended organizations. After the overall victory in the fight against poverty, the governance of relative poverty still requires continuous attention. Through our research, we hope to contribute to a better construction of a new poverty reduction system under the new poverty model. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

The characteristics of hand Verruca vulgaris in Tibetan adolescents in Ganzi county

Objective: To analyse the prevalence and characteristics about viral warts on the hands of Tibetan adolescents in Ganzi County.

SARS-CoV-2 specific antibody levels after a third dose of inactivated vaccine among 91 medical staff in Chengdu

Objective: To analysis the production of SARS-CoV-2 antibody among medical staff in Public Health Clinical Center of Chengdu 1 month after a third dose of inactivated vaccine (booster shot), and to compare the SARS-CoV-2 antibody among COVID-19 patients after immunization, in order to analyze the effect of the booster shot.

Anxiety of hearing impaired students in special schools during COVID-19

Objective: To understand anxiety status among students with hearing loss under the epidemic of novel coronarirus pneumonia, and to provide evidence for promoting mental health of hearing impaired students.